I have read in many places that transgender people are usually people who are born with typical male or female anatomies but feel as though they've been born into the “wrong bodies.” The thing that I am confused about is that how someone can not be considered as normal just because he thinks he should not be what he is? I met a female who looked exactly like a normal female and she was very beautiful. She didn't know that she was a transgender till her mom told her that she was transgender when she became adult. What is biological difference between a transgender and a normal male/female?
Answer
Remi gives a good introduction to the various terms and definitions you should know when learning about gender identity. However, he didn't really address your basic question:
What is biological difference between transgender and a normal male/female[?]
Except for some likely genetic differences, which we aren't even close to beginning to understand, there is no biological difference between two persons born with $XX$ sex chromosomes, one of whom identifies as female (cis-gender) and one of whom identifies as male, or somewhere on the spectrum between female and male (trans-gender). There is no difference physically - both have the same organs, including sex organs, and both have the same secondary sex characteristics. One cannot tell the difference upon gross physical examination, X-ray, blood test, etc. Gender is a social construction, and while the majority of people in the West have a gender identity that matches their biological sex, some do not, for reasons that are not yet clear.
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