Wednesday, 25 December 2019

evolution - Inbreeding Coefficient and Coefficient of Relationship


Wikipedia gives the following formula to calculate a "path of coefficient of relationship" between an ancestor $A$ and an offspring $O$:


$$\rho_{AO} = 2^{-n} \left( \frac{1+f_A}{1+f_O} \right)^{1/2} = \left( \frac{1}{2}\right)^n \sqrt { \frac{1+f_A}{1+f_O}}$$


, where $f_A$ and $f_O$ are the coefficient of inbreeding of the ancestor and the offspring respectively.




Question


Where does the term $\sqrt { \frac{1+f_A}{1+f_O}}$ comes from? Please explain why this multiplicative term is $\sqrt { \frac{1+f_A}{1+f_O}}$ and not something different such as $\frac{f_A f_O}{2}$ for example.




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