Wednesday, 25 December 2019

evolution - Inbreeding Coefficient and Coefficient of Relationship


Wikipedia gives the following formula to calculate a "path of coefficient of relationship" between an ancestor A and an offspring O:


ρAO=2n(1+fA1+fO)1/2=(12)n1+fA1+fO


, where fA and fO are the coefficient of inbreeding of the ancestor and the offspring respectively.




Question


Where does the term 1+fA1+fO comes from? Please explain why this multiplicative term is 1+fA1+fO and not something different such as fAfO2 for example.




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