Saturday 10 February 2018

Does protein structure depend on phylogeny?



Proteins have two basic secondary structure forms - beta strand and alpha helix. Do these depend on the organism or do the two forms exist for every protein?


For tertiary and quaternary structure: do such motifs depend on the position or does each organism have a specific form of protein structure?




Answer



Beta sheets and alpha helix are secondary structures that are simply very common to proteins. Their formation depends on the Amino acids that make up particular stretch in the primary sequence. For example alanines in a row will naturally tend to twist up into a alpha helix in water (medium matters). There are no hard and set rules to determine Tert. Structure or quart (aside from modeling but you have to validate in the end so its not entire end case)


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