Thursday, 10 November 2016

mitosis - Time spent in phases of cell cycle


I am looking for references to papers containing the time intervals spent in different phases of the cell cycle (ej., G0, G1, S, G2, M for eukaryotes) for different cells. In particular, I am interested in E. coli and CHO (Chinese Hamster Ovary cells), but any reference to studies of this kind for any typical cell will be useful.


I'll accept an answer containing a representative sample of references to the literature on this subject. Preferably recent papers (since 2010).


If you can provide the times spent in each phase but don't have references at hand, that will also be useful.



Answer



This is the data for a few cell types:




Cell type Total G1 S G2 M Ref
----------------------------------------------------------
Neuro2a 9 2 5 1.5 0.5 [1]
Hela 16.2 7.7 7.2 0.8 0.5 [2]
A549 18 7 7.5 2.5 1 [3]
MCF7 21.3 9 9.3 2 1 [4]
CHO 15 6 6.8 1.2 0.65 [5]

The timescale is in hours.





References:

  1. De Laat et al. 1980

  2. Kumei et al. 1989

  3. Orfanoudakis et al. 1989

  4. Taylor et al. 1983

  5. Harada and Morris 1981


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