I received a decision on my manuscript, requiring Major Revisions. One referee thinks one of my result is abnormal and contradictory with previous findings.
After checking my raw data and analysis and I found I did make a big mistake about the calculation. I know my carelessness brought the confusion to the referees and editors and I will explain this carefully in the cover letter when submitting the revised manuscript.
But I am also worried that the manuscript will be rejected even if I correct this mistake, because one mistake may make them stop trusting my research. How do editors and reviewers typically react to major changes in analysis?
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