Tuesday 15 January 2019

neuroscience - Why do neurons die so quickly (relative to other cells) when deprived of oxygen?


This question could be considered a follow-up question to Why is a lack of oxygen fatal to cells?, although the top answer there does not address why damage starts to pop in.



The answer says this:



Neurons are also highly metabolically active, which means they generate more waste products. A buildup of nitrogenous waste products in the cell (and bloodstream) can be potentially fatal due to it's effects on pH (screws up enzymes and a whole slew of biochemical reactions)



But when the brain is deprived of oxygen, metabolism shuts down. So waste products aren't being generated anymore.


====


Basically I'm wondering - what causes neurons, in particular, to die so quickly (relative to other cells, like kidney cells) after they're depleted of energy?




No comments:

Post a Comment

evolution - Are there any multicellular forms of life which exist without consuming other forms of life in some manner?

The title is the question. If additional specificity is needed I will add clarification here. Are there any multicellular forms of life whic...